Biology: The Dynamic Science (MindTap Course List)
Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Chapter 14, Problem 8TYK
Summary Introduction

Introduction:

Telomeres are short sequence of noncoding DNA or deoxyribonucleic acid at the end of eukaryotic chromosomes. These are repeated hundred to thousand times. Telomerase is a ribonucleoprotein that adds telomeres to the DNA strands.

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A research laboratory uses a cancer cell line that has undergone thousands of cell cycle divisions in the laboratory without any change in the length of its chromosomes. The most likely reason the chromosomes aren’t shortening is that the cancer cells are expressing Select one: a. very low levels of telomerase. b. high levels of telomerase. c. high levels of RNA polymerase. d. DNA polymerases with high fidelity. e. high levels of ligase activity.
The role of p53 in normal cells is toa. create cancer-blocking mutations.b. trigger unrestrained cell division.c. detect damaged DNA.d. splice exons together in the correct sequence.
Which of the following are characteristics of aging cells (select all that apply)? A. Chronic inflammation results in premature shortening of telomeres B. Lengthening of telomeric DNA sequence C. Accumulation of telomere-dysfunction–induced foci (TIFs) D. Older cells produce more telomerase E. Increased erosion of telomeres
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